Designed for high-sensitivity detection including fluorescent and luminescent detection, where extremely low backgrounds with no cross talk are needed. MatriPlate microplates demonstrated very low background levels in both green and blue channels, with excellent plate and well flatness, no leaks, no cytotoxicity, no significant edge effects, and excellent assay metrics.
Matrical Bioscience glass bottom microplates are both optically clear and extremely flat to ensure confluence and planarity for imaging devices to eliminate autofocus failures. Manufacturing and quality programs tightly control the production and validation to ensure the highest level of error-free performance with all automated assay instrumentation.
96 well and 384 well MatriPlate microplates with 0.17 and 0.72 mm bottom thicknesses have been used successfully with a variety of different cell types in many biological applications. MatriPlate glass bottom optical imaging plates offer exceptional quality for high-content cell based assays using imaging systems such as the IN Cell Analyzer 1000, ImageXpress, Array Scan, LEAP in process, IsoCyte, and Opera analyzing and high content screening systems.
Features:
Black or white polystyrene upper microplate structure.
MatriPlate microtiter microplates bottom surface options: 0.72 or 0.17mm glass.
Glass bottom microtiter microplates are scratch resistant.
Glass bottom microtiter microplates are microbubble resistant.
Rounded square microwells to eliminate liquid wicking.
Unmatched imaging bottom flatness with individual window flatness better than 2 microns over a 0.75mm.
Native charged surfaces allow many cell lines will adhere without surface treatments.
When a special surface treatment is required, we offer the variety of coating options including poly D lysine, collagen, fibronectin, supercoating, streptavidin, piranha wash, and much more!
In two-photon work, the excitation energy is sufficiently intense at the coverslip-buffer interface (where the cells grow) that microbubbles are formed in the plastic. These have an obvious negative impact on the image quality. Glass does not suffer this problem. Read more
Publications:
Comparison of g-protein coupled receptor desensitization-related arrestin redistribution using confocal and non-confocal imaging
Large scale screening for fluoresecent protein relocalization in yeast
Destruction of polymer growth substrates for cell cultures in two photon microscopy
